Bioorganic Chemistry

Course Code:

CHBE204

Course Period:

Spring

Course Type:

Core

Credits:

3

Theoric:

2

Practice:

0

Laboratory Hour:

2

ECTS:

5

Prerequisite Courses:

Organic Chemistry

Course Language:

English

Courses given by:

Erde Can Şafak

Course Objectives:

The aim of this course is to provide students with a knowledge of the chemicals of life (carbohydrates, lipids, amino acids, proteins, nucleic acids etc.): their structures, characteristics, chemical reactions and functions in the body and an ability for their qualitative and quantitative analysis.

Course Content:

Chemicals of life, carbohydrates, classification, properties and chemical reactions; lipids, general characteristics, fatty acids, fats and oils, waxes, glycerophospholipids, sphingolipids, steroids, cell membranes; aminoacids , electrophoresis, peptides and proteins, protein structure, denaturation; nucleic acids ,nucleosides and nucleotides, DNA and RNA. DNA replication. types of RNA. Term project.

Course Methodology:

1: Lecture, 2: Question-Answer, 3: Lab, 4: Case-study

Course Evaluation Methods:

A: Testing, B: Experiment, C: Homework, D: Project

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Course Learning Outcomes

Course Learning Outcomes	Program Learning Outcomes	Teaching Methods	Assessment Methods
1) Adequate knowledge of the chemicals of life (carbohydrates, lipids, aminoa acids, proteins, nucleic acids etc.): structures, characteristics and, chemical reactions and ability to use theoretical and applied information in these areas for their functions in the body, and their qualitative and quantitative analysis	1a,5b,c,d	1,2,3	A,B
2) Ability to conduct experiments, gather data, analyze and interpret results for chemical reactions, qualitative and quantitative analysis of carbohydrates, lipids and amino acids	5b,c,d	1,3	A,B
3) Ability to access information and to follow developments in the field of chemicals of life, their interactions in the body, effects on health and applications in drug, cosmetics, food and biofuels.	8	1,4	A,D
4) Ability to work efficiently in intra-disciplinary teams in term projects and in laboratory experiments and ability to communicate effectively both orally and in writing (via laboratory reports and project reports and presentations)	6a,7 b, c, e	1,3	B,D

Course Flow

COURSE CONTENT
Week	Topics	Study Materials
1	STEREOCHEMISTRY	Textbook
2	CARBOHYDRATES I (CHEMICAL STRUCTURES, CLASSIFICATION, FISCHER PROJECTIONS)	Textbook
3	CARBOHYDRATES II (CHARACTERISTICS, CYCLIC STRUCTURES, CHEMICAL REACTIONS)	Textbook
4	LIPIDS I (CLASSIFICATION, OILS AND FATS, WAXES)	Textbook
5	LIPIDS II (CHEMICAL REACTIONS, PHOSPHOLIPIDS, STEREOIDS, CELL MEMBRANE)	Textbook
6	MIDTERM EXAM I	Textbook
7	AMINO ACIDS, PROTEINS, PEPTIDES	Textbook
8	PROTEIN STRUCTURE, PRIMARY, SECONDARY, TERTIARY AND QUARTERNARY LEVELS	Textbook
9	PROTEIN HYDROLYSIS VE DENATURATION	Textbook
10	NUCLEIC ACIDS	Textbook
11	NUCLEOSIDES, NUCLEOTIDES	Textbook
12	MIDTERM EXAM II	Textbook
13	DNA, RNA, TYPES OF RNA	Textbook
14	POSTER PRESENTATION	Textbook

Recommended Sources

RECOMMENDED SOURCES

Textbook

Lab material: BIOORGANIC CHEMISTRY LABORATORY HANDBOOK

(Yeditepe University)

Additional Resources

CAREY,F.A. , “ORGANIC CHEMISTRY”, 9th Ed., McGRAW-HILL (TEXTBOOK)

TIMBERLAKE,K.C., “GENERAL, ORGANIC AND BIOLOGICAL CHEMISTRY”, 4th Ed.,PRENTICE HALL.

Mc MURRY, J., “ORGANIC CHEMISTRY”, 7th Ed,BROOKS/COLE

Assessment

ASSESSMENT
IN-TERM STUDIES	NUMBER	PERCENTAGE
Mid-terms	2	40
Lab Work	8	20
Term Project (Poster and Presentations)	1	5
Total		65
CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE		35
CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE		65
Total		100

Course’s Contribution to Program

COURSE'S CONTRIBUTION TO PROGRAM
No	Program Learning Outcomes	Contribution
No	Program Learning Outcomes	1	2	3	4	5
1	Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline; ability to use theoretical and applied information in these areas to model and solve engineering problems.					X
2	Ability to identify, formulate, and solve complex engineering problems; ability to select and apply proper analysis and modeling methods for this purpose.
3	Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the desired result; ability to apply modern design methods for this purpose.
4	Ability to devise, select, and use modern techniques and tools needed for engineering practice; ability to employ information technologies effectively.
5	Ability to design and conduct experiments, gather data, analyze and interpret results for investigating engineering problems.					X
6	Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.					X
7	Ability to communicate effectively both orally and in writing; knowledge of a minimum of one foreign language.					X
8	Recognition of the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.					X
9	Awareness of professional and ethical responsibility.				x
10	Information about business life practices such as project management, risk management, and change management; awareness of entrepreneurship, innovation, and sustainable development.
11	Knowledge about contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; awareness of the legal consequences of engineering solutions.

ECTS

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Course Duration (Including the exam weeks: 14x Total lecture hours)	14	2	28
Laboratory	9	2	18
Hours for off-the-classroom study (Pre-study, practice)	14	2	28
Laboratory Experiment and Report Preprations	8	5	40
Homework-Project	1	11	11
Final examination	1	2	2
Total Work Load			127
Total Work Load / 25 (h)			25
ECTS Credit of the Course			5

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