Experimental Genetics And Bioengineering I: Principles

Course Code:

GBE326

Course Period:

Spring

Course Type:

Core

Credits:

3

Theoric:

2

Practice:

0

Laboratory Hour:

2

ECTS:

6

Prerequisite Courses:

Biothermodynamics

Course Language:

English

Course Coordinator:

Zeynep İşlek Köklü

Courses given by:

Zeynep İşlek Köklü

Course Objectives:

To understand the fundamentals of bioprocess engineering with separation and purification systems.

Course Content:

Bioprocess engineering, the kinetics of enzyme and microorganisms, bioreactors, separation and purification systems

Course Methodology:

1: Lecture by instructor, 2: Lecture by instructor with class discussion, 3: Problem solving by instructor, 4: Use of simulations, 5: Problem solving assignment, 6: Reading assignment, 7: Laboratory work, 8: Term research paper, 9: Presentation by guest s

Course Evaluation Methods:

A: Written exam, B: Multiple-choice exam C: Take-home quiz, D: Experiment report, E: Homework, F: Project, G: Presentation by student, H: …

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Course Learning Outcomes

Course Learning Outcomes	Detailed Program Outcomes	Teaching Methods	Assessment Methods
Ability to understand the correlation between biology and engineering themes	1a, 1b, 7b, 10a, 11a	1, 3, 5, 7	A, D
Ability to understand the basics of bioprocess engineering	1b, 2a, 2b, 4a, 5a, 5b, 6a, 7c, 7e, 10a, 11a	1, 3, 7	A, D, E
Ability to use bioprocess kinetics to evaluate the performance of bioprocesses	2a, 2b, 4a, 5a, 5b, 6a, 7c, 7e,	1, 3, 5, 7	A, D, E
Ability to understand the bioreactor design how to effect microorganism/cell growth and production	2a, 2b, 4a, 5a, 5b, 6a, 7c, 7e,	1, 3, 7	A, D
Ability to understand the downstream processes for importance of bioprocess engineering	2a, 2b, 4a, 5a, 5b, 6a, 7c, 7e,	1, 3, 7	A, D

Course Flow

COURSE CONTENT
Week	Topics	Study Materials
1	Introduction of Bioprocess Engineering	Textbook
2	Bioprocess Engineering	Textbook
3	Bioprocess Engineering	Textbook
4	Bioprocess Engineering and Kinetics	Textbook
5	Kinetics	Textbook
6	Kinetics	Textbook
7	Mid-term	Textbook
8	Bioreactors and Experiment: Isolation of Microorganisms	Textbook
9	Bioreactors and Experment: Screening of Microorganisms	Textbook
10	Bioreactors and Experiments: Enzyme Stability and Optimum Conditions	Textbook
11	Downstream processes and Experiment: Media Optimization	Textbook
12	Downstream processes and Experiment: Cell degradation	Textbook
13	Downstream processes and Experiment: Separation and Purification	Textbook
14	Downstream processes and Experiment: Immobilization	Textbook
15	Downstream processes	Textbook

Recommended Sources

RECOMMENDED SOURCES
Textbook	Biochemical Engineering Fundamentals, Bailey & Ollis, 4th Ed.
Additional Resources

Material Sharing

MATERIAL SHARING
Documents	Lecture slides are sharing with students via Moodle
Assignments	Experiment reports should be submitted within a week after experiment
Exams	1 midterm and 1 final.

Assessment

ASSESSMENT
IN-TERM STUDIES	NUMBER	PERCENTAGE
Mid-Term	1	30
Laboratory	7	25
Total		55
CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE	1	45
CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE		55
Total		100

Course’s Contribution to Program

COURSE'S CONTRIBUTION TO PROGRAM OUTCOMES
No	Program Learning Outcomes	check √
1a	Adequate knowledge in mathematics, science and engineering subjects pertaining to the relevant discipline,	X
1b	Ability to use theoretical and applied knowledge in these areas in complex engineering problems.	X
2a	Ability to identify, formulate, and solve complex engineering problems,	X
2b	Ability to select and apply proper analysis and modeling methods for this purpose.	X
3a	Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the desired result,
3b	Ability to apply modern design methods for this purpose.
4a	Ability to devise, select and use modern techniques and tools needed for analyzing and solving complex problems encountered in engineering practice.	X
4b	Ability to employ information technologies effectively.
5a	Ability to design experiments for investigating complex engineering problems or discipline specific research questions,	X
5b	Ability to conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or discipline specific research questions.	X
6a	Ability to work efficiently in intra-disciplinary teams,	X
6b	Ability to work efficiently in multi-disciplinary teams,
6c	Ability to work individually.
7a	Ability to communicate effectively in Turkish, both orally and in writing,
7b	Knowledge of a minimum of one foreign language,	X
7c	Ability to write effective reports and comprehend written reports, prepare design and production reports,	X
7d	Ability to make effective presentations,
7e	Ability to give and receive clear and intelligible instructions.	X
8a	Recognition of the need for lifelong learning, ability to access information, ability to follow developments in science and technology,
8b	Ability to continue to educate him/herself.
9a	Consciousness to behave according to ethical principles and professional and ethical responsibility.
9b	Knowledge on standards used in engineering practice.	X
10a	Knowledge about business life practices such as project management, risk management, change management.
10b	Awareness in entrepreneurship and innovation.
10c	Knowledge about sustainable development.
11a	Knowledge about the global and social effects of engineering practices on health, environment, and safety,	X
11b	Knowledge about contemporary issues of the century reflected into the field of engineering.
11c	Awareness of the legal consequences of engineering solutions.

ECTS

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
Activities	Quantity	Duration (Hour)	Total Workload (Hour)
Course Duration	14	4	56
Hours for off-the-classroom study (Pre-study, practice)	7	8	56
Mid-Term examination	1	2	2
Final examination	1	3	3
Total Work Load			117
Total Work Load / 25 (h)			4.68
ECTS Credit of the Course			5

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Experimental Genetics And Bioengineering I: Principles

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